Ontology highlight
ABSTRACT:
SUBMITTER: Yamasaki S
PROVIDER: S-EPMC4569093 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Archives of virology 20100521 7
Human adenovirus 40 (Ad40) is an interesting candidate for vector construction because of its tropism for the gastrointestinal tract. Although effective preparation of the vector is necessary for its in vivo application, amplification of Ad40 has been very difficult. Ad40 E1 deletion mutants were detected by PCR in the viral DNA from Ad40 Dugan amplified by Ad5 E1-expressing human embryonic kidney (293) cells and in Ad40 Dugan plaques observed with Ad5 E1-expressing human retinoblastic cells. Fo ...[more]