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Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls.

ABSTRACT: Common polymorphisms of microRNA gene MIR146A were reported as associated with different autoimmune diseases, include systemic lupus erythematosus, psoriatic arthritis, asthma and ankylosing spondylitis. In this study we investigated MIR146A SNPs in Chinese people with ankylosing spondylitis. Three common SNPs: rs2910164, rs2431697 and rs57095329 were selected and genotyped in 611 patients and 617 controls. We found no association between these SNPs and ankylosing spondylitis in our samples.

SUBMITTER: Niu Z

PROVIDER: S-EPMC4569555 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls.

Niu Zhenmin Z Wang Jiucun J Zou Hejian H Yang Chengde C Huang Wei W Jin Li L

PloS one 20150914 9

Common polymorphisms of microRNA gene MIR146A were reported as associated with different autoimmune diseases, include systemic lupus erythematosus, psoriatic arthritis, asthma and ankylosing spondylitis. In this study we investigated MIR146A SNPs in Chinese people with ankylosing spondylitis. Three common SNPs: rs2910164, rs2431697 and rs57095329 were selected and genotyped in 611 patients and 617 controls. We found no association between these SNPs and ankylosing spondylitis in our samples. ...[more]

PMID: 26366721

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