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Extensive Recruitment of Plasma Blasts to the Cerebrospinal Fluid in Toscana Virus Encephalitis.


ABSTRACT: An unexpectedly extensive recruitment of B cells and plasma blasts to the cerebrospinal fluid (CSF) in a patient with Toscana virus (TOSV) encephalitis is described. Acute infection by TOSV was demonstrated by serological methods and by detection of TOSV-specific nucleic acid in the CSF by real-time polymerase chain reaction and sequencing.

SUBMITTER: Schirmer L 

PROVIDER: S-EPMC4569839 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature

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Extensive Recruitment of Plasma Blasts to the Cerebrospinal Fluid in Toscana Virus Encephalitis.

Schirmer Lucas L   Wölfel Silke S   Georgi Enrico E   Ploner Markus M   Bauer Barbara B   Hemmer Bernhard B  

Open forum infectious diseases 20150901 3


An unexpectedly extensive recruitment of B cells and plasma blasts to the cerebrospinal fluid (CSF) in a patient with Toscana virus (TOSV) encephalitis is described. Acute infection by TOSV was demonstrated by serological methods and by detection of TOSV-specific nucleic acid in the CSF by real-time polymerase chain reaction and sequencing. ...[more]

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