Ontology highlight
ABSTRACT:
SUBMITTER: AbuSamra DB
PROVIDER: S-EPMC4571854 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
AbuSamra Dina B DB Al-Kilani Alia A Hamdan Samir M SM Sakashita Kosuke K Gadhoum Samah Z SZ Merzaban Jasmeen S JS
The Journal of biological chemistry 20150629 35
Selectins (E-, P-, and L-selectins) interact with glycoprotein ligands to mediate the essential tethering/rolling step in cell transport and delivery that captures migrating cells from the circulating flow. In this work, we developed a real time immunoprecipitation assay on a surface plasmon resonance chip that captures native glycoforms of two well known E-selectin ligands (CD44/hematopoietic cell E-/L-selectin ligand and P-selectin glycoprotein ligand-1) from hematopoietic cell extracts. Here ...[more]