New insights into craniofacial malformations.
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ABSTRACT:
SUBMITTER: Twigg SR
PROVIDER: S-EPMC4571997 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Publications
New insights into craniofacial malformations.
Twigg Stephen R F SR Wilkie Andrew O M AO
Human molecular genetics 20150617 R1
Development of the human skull and face is a highly orchestrated and complex three-dimensional morphogenetic process, involving hundreds of genes controlling the coordinated patterning, proliferation and differentiation of tissues having multiple embryological origins. Craniofacial malformations that occur because of abnormal development (including cleft lip and/or palate, craniosynostosis and facial dysostoses), comprise over one-third of all congenital birth defects. High-throughput sequencing ...[more]
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