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Evaluation of food products fortified with oyster shell for the prevention and treatment of osteoporosis.

ABSTRACT: Production and evaluation of different diet formulas fortified with oyster shell for the prevention and treatment of osteoporosis. Eighty-eight female albino rats were recruited and divided into 11 groups (8 rats each). Group 1 represented negative control while the remaining groups were ovariectomized. Group 2 acted as positive control. Groups 3-5 were fed on basal diet. Groups 6-8 were fed on lentil soup while groups 9-11 were fed on vegetable soup. Group 4, 7, 10 were fed on diets fortified with oyster shell. Groups 5, 8 and 11 were fed on diet formulas fortified with calcium citrate. All calcium fortified diet formulas, especially lentil soup, have minimized risk factors associated with osteoporosis as indicated from the significant increase in tibial weight, total protein, total calcium and phosphorus with noticeable reduction in ALP activity compared to positive group. Maximum recovery was observed for diet fortified with oyster shell. These data suggest that food products fortified with oyster shell as natural and inexpensive source could be beneficial for the prevention and treatment of osteoporosis.

SUBMITTER: Ahmed SA

PROVIDER: S-EPMC4573138 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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Evaluation of food products fortified with oyster shell for the prevention and treatment of osteoporosis.

Ahmed S A SA Gibriel Abdullah A Y AA Abdellatif A K AK Ebied H M HM

Journal of food science and technology 20150121 10

Production and evaluation of different diet formulas fortified with oyster shell for the prevention and treatment of osteoporosis. Eighty-eight female albino rats were recruited and divided into 11 groups (8 rats each). Group 1 represented negative control while the remaining groups were ovariectomized. Group 2 acted as positive control. Groups 3-5 were fed on basal diet. Groups 6-8 were fed on lentil soup while groups 9-11 were fed on vegetable soup. Group 4, 7, 10 were fed on diets fortified w ...[more]

PMID: 26396435

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Project description:IntroductionMicronutrient (MN) deficiencies cause a considerable burden of disease for children in many countries. Dairy products or cereals are an important food component during adolescence. Fortification of dairy products or cereals with MN may be an effective strategy to overcome MN deficiencies, but their specific impact on health in this age group is poorly documented.MethodsWe performed a systematic review and meta-analysis (registration number CRD42016039554) to assess the impact of MN fortified dairy products and cereal food on the health of children and adolescents (aged 5-15 years) compared with non-fortified food. We reviewed randomised controlled trials (RCT) using electronic databases (MEDLINE, EMBASE, Cochrane library; latest search: January 2018), reference list screening and citation searches. Three pairs of reviewers assessed 2048 studies for eligibility and extracted data. We assessed the risk of bias and applied GRADE to rate quality of evidence.ResultsWe included 24 RCT (often multi MN fortification) with 30 pair-wise comparisons mainly from low- and middle income countries. A very small and non-significant increase of haemoglobin values emerged (0.09 g/dl [95%-CI: -0.01 to 0.18]; 13 RCT with iron fortification; very low quality of evidence). No significant difference was found on anaemia risk (risk ratio 0.87 [95%-CI: 0.76 to 1.01]; 12 RCT; very low quality), but a significant difference in iron deficiency anaemia favouring fortified food was found (risk ratio 0.38 [95%-CI: 0.18 to 0.81]; 5 RCT; very low quality). Similar effects were seen for fortified dairy products and cereals and different fortification strategies (mono- vs. dual- vs. multi-MN). Follow-up periods were often short and the impact on anthropometric measures was weak (low quality of evidence) Very low quality of evidence emerged for the improvement of cognitive performance, functional measures and morbidity.ConclusionsFortification of dairy products and cereal food had only marginal health effects in our sample population from 5-15 years. Further evidence is needed to better understand the health impact of fortified dairy products and cereals in this age group.Systematic review registrationThe study protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on 26 May 2016 (registration number CRD42016039554).

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Evaluation of food products fortified with oyster shell for the prevention and treatment of osteoporosis.

Publications

Evaluation of food products fortified with oyster shell for the prevention and treatment of osteoporosis.

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