Ontology highlight
ABSTRACT:
SUBMITTER: Breitling C
PROVIDER: S-EPMC4573320 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Breitling Clara C Gross Arnd A Büttner Petra P Weise Sebastian S Schleinitz Dorit D Kiess Wieland W Scholz Markus M Kovacs Peter P Körner Antje A
PloS one 20150916 9
<h4>Objective</h4>To assess potential effects of variants in six lipid modulating genes (SORT1, HMGCR, MLXIPL, FADS2, APOE and MAFB) on early development of dyslipidemia independent of the degree of obesity in children, we investigated their association with total (TC), low density lipoprotein (LDL-C), high density lipoprotein (HDL-C) cholesterol and triglyceride (TG) levels in 594 children. Furthermore, we evaluated the expression profile of the candidate genes during human adipocyte differenti ...[more]