Ontology highlight
ABSTRACT:
SUBMITTER: Kang HG
PROVIDER: S-EPMC4573440 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Kang Hee Gyung HG Cheong Hae Il HI
Korean journal of pediatrics 20150821 8
While the incidence of nephrotic syndrome (NS) is decreasing in Korea, the morbidity of difficult-to-treat NS is significant. Efforts to minimize treatment toxicity showed that prolonged treatment after an initial treatment for 2-3 months with glucocorticosteroids was not effective in reducing frequent relapses. For steroid-dependent NS, rituximab, a monoclonal antibody against the CD20 antigen on B cells, was proven to be as effective, and short-term daily low-dose steroids during upper respira ...[more]