Ontology highlight
ABSTRACT:
SUBMITTER: Cheng X
PROVIDER: S-EPMC4576204 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Viruses 20150820 8
Transcription activator-like effectors (TALEs) are a class of sequence-specific DNA-binding proteins that utilize a simple and predictable modality to recognize target DNA. This unique characteristic allows for the rapid assembly of artificial TALEs, with high DNA binding specificity, to any target DNA sequences for the creation of customizable sequence-specific nucleases used in genome engineering. Here, we report the use of an artificial TALE protein as a convenient platform for designing broa ...[more]