Effects of BKCa and Kir2.1 Channels on Cell Cycling Progression and Migration in Human Cardiac c-kit+ Progenitor Cells.
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ABSTRACT:
SUBMITTER: Zhang YY
PROVIDER: S-EPMC4577111 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Effects of BKCa and Kir2.1 Channels on Cell Cycling Progression and Migration in Human Cardiac c-kit+ Progenitor Cells.
Zhang Ying-Ying YY Li Gang G Che Hui H Sun Hai-Ying HY Xiao Guo-Sheng GS Wang Yan Y Li Gui-Rong GR
PloS one 20150921 9
Our previous study demonstrated that a large-conductance Ca2+-activated K+ current (BKCa), a voltage-gated TTX-sensitive sodium current (INa.TTX), and an inward rectifier K+ current (IKir) were heterogeneously present in most of human cardiac c-kit+ progenitor cells. The present study was designed to investigate the effects of these ion channels on cell cycling progression and migration of human cardiac c-kit+ progenitor cells with approaches of cell proliferation and mobility assays, siRNA, RT- ...[more]
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