Ontology highlight
ABSTRACT:
SUBMITTER: Suess DL
PROVIDER: S-EPMC4577183 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Suess Daniel L M DL Bürstel Ingmar I De La Paz Liliana L Kuchenreuther Jon M JM Pham Cindy C CC Cramer Stephen P SP Swartz James R JR Britt R David RD
Proceedings of the National Academy of Sciences of the United States of America 20150831 37
Hydrogenases catalyze the redox interconversion of protons and H2, an important reaction for a number of metabolic processes and for solar fuel production. In FeFe hydrogenases, catalysis occurs at the H cluster, a metallocofactor comprising a [4Fe-4S]H subcluster coupled to a [2Fe]H subcluster bound by CO, CN(-), and azadithiolate ligands. The [2Fe]H subcluster is assembled by the maturases HydE, HydF, and HydG. HydG is a member of the radical S-adenosyl-L-methionine family of enzymes that tran ...[more]