Ontology highlight
ABSTRACT:
SUBMITTER: Bella M
PROVIDER: S-EPMC4578356 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Bella Maroš M Koóš Miroslav M Lin Chun-Hung CH
Beilstein journal of organic chemistry 20150904
A novel synthetic strategy leading to 3-acetamido-3-deoxy-D-psicofuranose 9 is presented. The latter compound, after some manipulations, was transformed into fully protected 3-acetamido-3-deoxy-D-psicofuranose 11 as a potential substrate for the synthesis of N-acetylglucosaminyltransferase inhibitors designed by computational methods. After the attempted thioglycosylation of 11 with EtSH in the presence of BF3·OEt2, 2-methyloxazoline derivatives 13 and 14 were isolated. ...[more]