Ontology highlight
ABSTRACT:
SUBMITTER: Wang S
PROVIDER: S-EPMC4581195 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Wang Sheng S Weng Shunyan S Ma Jianzhu J Tang Qingming Q
International journal of molecular sciences 20150729 8
Intrinsically disordered proteins or protein regions are involved in key biological processes including regulation of transcription, signal transduction, and alternative splicing. Accurately predicting order/disorder regions ab initio from the protein sequence is a prerequisite step for further analysis of functions and mechanisms for these disordered regions. This work presents a learning method, weighted DeepCNF (Deep Convolutional Neural Fields), to improve the accuracy of order/disorder pred ...[more]