Ontology highlight
ABSTRACT:
SUBMITTER: Simeon V
PROVIDER: S-EPMC4581206 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Simeon Vittorio V Todoerti Katia K La Rocca Francesco F Caivano Antonella A Trino Stefania S Lionetti Marta M Agnelli Luca L De Luca Luciana L Laurenzana Ilaria I Neri Antonino A Musto Pellegrino P
International journal of molecular sciences 20150730 8
Primary plasma cell leukemia (pPCL) is a rare and aggressive variant of multiple myeloma (MM) which may represent a valid model for high-risk MM. This disease is associated with a very poor prognosis, and unfortunately, it has not significantly improved during the last three decades. New high-throughput technologies have allowed a better understanding of the molecular basis of this disease and moved toward risk stratification, providing insights for targeted therapy studies. This knowledge, adde ...[more]