Ontology highlight
ABSTRACT:
SUBMITTER: Dumoux M
PROVIDER: S-EPMC4582400 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Journal of cell science 20150728 18
The obligate intracellular bacterial pathogen Chlamydia trachomatis deploys virulence effectors to subvert host cell functions enabling its replication within a specialized membrane-bound compartment termed an inclusion. The control of the host cytoskeleton is crucial for Chlamydia uptake, inclusion biogenesis and cell exit. Here, we demonstrate how a Chlamydia effector rearranges the microtubule (MT) network by initiating organization of the MTs at the inclusion surface. We identified an inclus ...[more]