Ontology highlight
ABSTRACT:
SUBMITTER: Parida SK
PROVIDER: S-EPMC4583575 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20151001
The emergence of drug-resistant tuberculosis is challenging tuberculosis control worldwide. In the absence of an effective vaccine to prevent primary infection with Mycobacterium tuberculosis and tuberculosis disease, host-directed therapies may offer therapeutic options, particularly for patients with multidrug-resistant and extensively drug-resistant tuberculosis where prognosis is often limited. CD8(+) and CD4(+) T cells mediate antigen-specific adaptive cellular immune responses. Their use i ...[more]