Pseudogenes in Human Cancer.
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ABSTRACT:
SUBMITTER: Poliseno L
PROVIDER: S-EPMC4585173 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Pseudogenes in Human Cancer.
Poliseno Laura L Marranci Andrea A Pandolfi Pier Paolo PP
Frontiers in medicine 20150925
Recent advances in the analysis of RNA sequencing data have shown that pseudogenes are highly specific markers of cell identity and can be used as diagnostic and prognostic markers. Furthermore, genetically engineered mouse models have recently provided compelling support for a causal link between altered pseudogene expression and cancer. In this review, we discuss the most recent milestones reached in the pseudogene field and the use of pseudogenes as cancer classifiers. ...[more]
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