Unknown

Dataset Information

0

Resting-State and Task-Based Functional Brain Connectivity in Developmental Dyslexia.


ABSTRACT: Reading requires the interaction between multiple cognitive processes situated in distant brain areas. This makes the study of functional brain connectivity highly relevant for understanding developmental dyslexia. We used seed-voxel correlation mapping to analyse connectivity in a left-hemispheric network for task-based and resting-state fMRI data. Our main finding was reduced connectivity in dyslexic readers between left posterior temporal areas (fusiform, inferior temporal, middle temporal, superior temporal) and the left inferior frontal gyrus. Reduced connectivity in these networks was consistently present for 2 reading-related tasks and for the resting state, showing a permanent disruption which is also present in the absence of explicit task demands and potential group differences in performance. Furthermore, we found that connectivity between multiple reading-related areas and areas of the default mode network, in particular the precuneus, was stronger in dyslexic compared with nonimpaired readers.

SUBMITTER: Schurz M 

PROVIDER: S-EPMC4585499 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

altmetric image

Publications

Resting-State and Task-Based Functional Brain Connectivity in Developmental Dyslexia.

Schurz Matthias M   Wimmer Heinz H   Richlan Fabio F   Ludersdorfer Philipp P   Klackl Johannes J   Kronbichler Martin M  

Cerebral cortex (New York, N.Y. : 1991) 20140828 10


Reading requires the interaction between multiple cognitive processes situated in distant brain areas. This makes the study of functional brain connectivity highly relevant for understanding developmental dyslexia. We used seed-voxel correlation mapping to analyse connectivity in a left-hemispheric network for task-based and resting-state fMRI data. Our main finding was reduced connectivity in dyslexic readers between left posterior temporal areas (fusiform, inferior temporal, middle temporal, s  ...[more]

Similar Datasets

| S-EPMC3625268 | biostudies-literature
| S-EPMC4238260 | biostudies-literature
| S-EPMC8196021 | biostudies-literature
| S-EPMC6231684 | biostudies-literature
| S-EPMC3980132 | biostudies-literature
| S-EPMC5053852 | biostudies-literature
| S-EPMC4791061 | biostudies-literature
| S-EPMC4461484 | biostudies-literature
| S-EPMC6866797 | biostudies-literature
| S-EPMC4076230 | biostudies-literature