Ontology highlight
ABSTRACT:
SUBMITTER: Kawai T
PROVIDER: S-EPMC4586460 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Kawai Tomoko T Yamada Takahiro T Abe Kosei K Okamura Kohji K Kamura Hiromi H Akaishi Rina R Minakami Hisanori H Nakabayashi Kazuhiko K Hata Kenichiro K
Scientific reports 20150929
Epigenetic modifications are thought to serve as a memory of exposure to in utero environments. However, few human studies have investigated the associations between maternal nutritional conditions during pregnancy and epigenetic alterations in offspring. In this study, we report genome-wide methylation profiles for 33 postpartum placentas from pregnancies of normal and foetal growth restriction with various extents of maternal gestational weight gain. Epigenetic alterations accumulate in the pl ...[more]