Ontology highlight
ABSTRACT:
SUBMITTER: Kampmann C
PROVIDER: S-EPMC4587871 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Orphanet journal of rare diseases 20150929
<h4>Background</h4>To explore long-term effects of agalsidase alfa on Fabry disease cardiomyopathy in adults.<h4>Methods</h4>Retrospective analysis of prospectively collected data at a single center in Mainz, Germany, revealed that 45 adult patients (21 men, 24 women) had received agalsidase alfa for approximately 10 years. Data were extracted for cardiac and heart failure status, echocardiographic evaluations of cardiac structure and function, and renal function at treatment start and during ag ...[more]