Ontology highlight
ABSTRACT:
SUBMITTER: Bagulho A
PROVIDER: S-EPMC4588420 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Bagulho Ana A Vilas-Boas Filipe F Pena Andreia A Peneda Catarina C Santos Filipa C FC Jerónimo Ana A de Almeida Rodrigo F M RFM Real Carla C
Redox biology 20150912
The molecular processes that are crucial for cell function, such as proliferation, migration and survival, are regulated by hydrogen peroxide (H2O2). Although environmental cues, such as growth factors, regulate redox signaling, it was still unknown whether the ECM, a component of the cell microenvironment, had a function in this process. Here, we showed that the extracellular matrix (ECM) differently regulated H2O2 consumption by endothelial cells and that this effect was not general for all ty ...[more]