High-definition fiber tractography for the evaluation of perilesional white matter tracts in high-grade glioma surgery.

ABSTRACT: Conventional white matter (WM) imaging approaches, such as diffusion tensor imaging (DTI), have been used to preoperatively identify the location of affected WM tracts in patients with intracranial tumors in order to maximize the extent of resection and potentially reduce postoperative morbidity. DTI, however, has limitations that include its inability to resolve multiple crossing fibers and its susceptibility to partial volume effects. Therefore, recent focus has shifted to more advanced WM imaging techniques such as high-definition fiber tractography (HDFT). In this paper, we illustrate the application of HDFT, which in our preliminary experience has enabled accurate depiction of perilesional tracts in a 3-dimensional manner in multiple anatomical compartments including edematous zones a

SUBMITTER: Abhinav K 

PROVIDER: S-EPMC4588761 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature