Ontology highlight
ABSTRACT:
SUBMITTER: Cregg R
PROVIDER: S-EPMC4590162 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
British journal of pain 20131101 4
• Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined. • Analgesics act in various ways on the peripheral and central pain pathways and are regarded as one of the most valuable but equally dangerous groups of medications. • While pharmacokinetic properties of drugs, metabolism in particular, have been scrutinised by genotype-phenotype correlation studies, the clinical significance of inherited ...[more]