Ontology highlight
ABSTRACT:
SUBMITTER: Tang-Feldman YJ
PROVIDER: S-EPMC4591060 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Tang-Feldman Yajarayma J YJ Lochhead Stephanie R SR Lochhead G Raymond GR Yu Cindy C George Michael M Villablanca Amparo C AC Pomeroy Claire C
Journal of cardiovascular translational research 20121129 1
Multiple studies suggest an association between cytomegalovirus (CMV) infection and atherogenesis; however, the molecular mechanisms by which viral infection might exacerbate atherosclerosis are not well understood. Aortas of MCMV-infected and uninfected Apo E knockout (KO) mice were analyzed for atherosclerotic lesion development and differential gene expression. Lesions in the infected mice were larger and showed more advanced disease compared to the uninfected mice. Sixty percent of the genes ...[more]