Memory systems in schizophrenia: Modularity is preserved but deficits are generalized.

ABSTRACT:

Objective

Schizophrenia patients exhibit impaired working and episodic memory, but this may represent generalized impairment across memory modalities or performance deficits restricted to particular memory systems in subgroups of patients. Furthermore, it is unclear whether deficits are unique from those associated with other disorders.

Method

Healthy controls (n=1101) and patients with schizophrenia (n=58), bipolar disorder (n=49) and attention-deficit-hyperactivity-disorder (n=46) performed 18 tasks addressing primarily verbal and spatial episodic and working memory. Effect sizes for group contrasts were compared across tasks and the consistency of subjects' distributional positions across memory domains was measured.

Results

Schizophrenia patients performed poorly

SUBMITTER: Haut KM 

PROVIDER: S-EPMC4591239 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature