Ontology highlight
ABSTRACT:
SUBMITTER: Dutta SK
PROVIDER: S-EPMC4594659 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Protein science : a publication of the Protein Society 20150730 10
Flavodoxins in combination with the flavin mononucleotide (FMN) cofactor play important roles for electron transport in prokaryotes. Here, novel insights into the FMN-binding mechanism to flavodoxins-4 were obtained from the NMR structures of the apo-protein from Lactobacillus acidophilus (YP_193882.1) and comparison of its complex with FMN. Extensive reversible conformational changes were observed upon FMN binding and release. The NMR structure of the FMN complex is in agreement with the crysta ...[more]