Epidemiological and Molecular Characterization of Invasive Meningococcal Disease in Italy, 2008/09-2012/13.

ABSTRACT:

Background

Following the introduction of meningococcal serogroup C conjugate vaccine in Italy in 2005, changes in the epidemiology of Invasive Meningococcal Disease (IMD) were expected. The study aims were to describe the epidemiological trend and to characterize the isolates collected during the period 2008/09-2012/13 by multilocus sequence typing (MLST). Data on laboratory confirmed meningococcal diseases from National Surveillance System of IMD were reported.

Methods

Poisson regression models were used to estimate the incidence rate over time. Serogrouping and MLST were performed following published methods.

Results

The incidence rate of laboratory confirmed meningococcal disease decreased from 0.33 per 100,000 population in 2008/09 to 0.25 per 100,000 population i

SUBMITTER: Neri A 

PROVIDER: S-EPMC4596568 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature