Modulation of Phenol Oxidation in Cofacial Dyads.
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ABSTRACT:
SUBMITTER: Koo BJ
PROVIDER: S-EPMC4596711 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Publications
Modulation of Phenol Oxidation in Cofacial Dyads.
Koo Bon Jun BJ Huynh Michael M Halbach Robert L RL Stubbe JoAnne J Nocera Daniel G DG
Journal of the American Chemical Society 20150909 37
The presentation of two phenols on a xanthene backbone is akin to the tyrosine dyad (Y730 and Y731) of ribonucleotide reductase. X-ray crystallography reveals that the two phenol moieties are cofacially disposed at 4.35 Å. Cyclic voltammetry reveals that phenol oxidation is modulated within the dyad, which exhibits a splitting of one-electron waves with the second oxidation of the phenol dyad occurring at larger positive potential than that of a typical phenol. In contrast, a single phenol appen ...[more]
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