Ontology highlight
ABSTRACT:
SUBMITTER: Hsueh YY
PROVIDER: S-EPMC4597209 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Hsueh Yuan-Yu YY Chang Ya-Ju YJ Huang Chia-Wei CW Handayani Fitri F Chiang Yi-Lun YL Fan Shih-Chen SC Ho Chien-Jung CJ Kuo Yu-Min YM Yang Shang-Hsun SH Chen Yuh-Ling YL Lin Sheng-Che SC Huang Chao-Ching CC Wu Chia-Ching CC
Scientific reports 20151008
Perinatal cerebral hypoxic-ischemic (HI) injury damages the architecture of neurovascular units (NVUs) and results in neurological disorders. Here, we differentiated adipose-derived stem cells (ASCs) toward the progenitor of endothelial progenitor cells (EPCs) and neural precursor cells (NPCs) via microenvironmental induction and investigated the protective effect by transplanting ASCs, EPCs, NPCs, or a combination of EPCs and NPCs (E+N) into neonatal HI injured rat pups. The E+N combination pro ...[more]