Efficacy and HIV drug resistance profile of second-line ART among patients having received long-term first-line regimens in rural China.
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ABSTRACT:
SUBMITTER: Wang J
PROVIDER: S-EPMC4597210 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
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Efficacy and HIV drug resistance profile of second-line ART among patients having received long-term first-line regimens in rural China.
Wang Jing J Wang Zhe Z Liu Jia J Yue Yanchao Y Yang Shimei S Huang Huimin H He Cui C Liao Lingjie L Xing Hui H Ruan Yuhua Y Shao Yiming Y
Scientific reports 20151008
Antiretroviral therapy has significantly expanded and an increased proportion of patients have switched to second-line regimens in China. We describe the outcomes of second-line therapy among patients having received long-term first-line ART. A prospective follow-up study was conducted in rural areas in China. We compared the virological, immunological outcomes and genotypic drug resistance (DR) profiles before and after regimen switches. A total of 303 patients were enrolled, 283 (93.4%) were r ...[more]
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| S-EPMC5300167 | biostudies-literature
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