Ontology highlight
ABSTRACT:
SUBMITTER: Chen CL
PROVIDER: S-EPMC4598150 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Chen Chun-Lin CL Chen Ying-Pin YP Lin Ming-Wei MW Huang Yaw-Bin YB Chang Fang-Rong FR Duh Tsai-Hui TH Wu Deng-Chyang DC Wu Wei-Chiang WC Kao Yu-Chen YC Yang Pei-Hua PH
PloS one 20151008 10
Transforming growth factor-β (TGF-β) responsiveness in cultured cells can be modulated by TGF-β partitioning between lipid raft/caveolae- and clathrin-mediated endocytosis pathways. Lipid rafts are plasma membrane microdomains with an important role in cell survival signaling, and cholesterol is necessary for the lipid rafts' structure and function. Euphol is a euphane-type triterpene alcohol that is structurally similar to cholesterol and has a wide range of pharmacological properties, includin ...[more]