Ontology highlight
ABSTRACT:
SUBMITTER: Gooskens SL
PROVIDER: S-EPMC4599240 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Gooskens Saskia L SL Gadd Samantha S Guidry Auvil Jaime M JM Gerhard Daniela S DS Khan Javed J Patidar Rajesh R Meerzaman Daoud D Chen Qing-Rong QR Hsu Chih Hao CH Yan Chunhua C Nguyen Cu C Hu Ying Y Mullighan Charles G CG Ma Jing J Jennings Lawrence J LJ de Krijger Ronald R RR van den Heuvel-Eibrink Marry M MM Smith Malcolm A MA Ross Nicole N Gastier-Foster Julie M JM Perlman Elizabeth J EJ
Oncotarget 20150601 18
Clear Cell Sarcoma of the Kidney (CCSK) is a rare childhood tumor whose molecular pathogenesis remains poorly understood. We analyzed a discovery set of 13 CCSKs for changes in chromosome copy number, mutations, rearrangements, global gene expression and global DNA methylation. No recurrent segmental chromosomal copy number changes or somatic variants (single nucleotide or small insertion/deletion) were identified. One tumor with t(10;17)(q22;p13) involving fusion of YHWAE with NUTM2B was identi ...[more]