Ontology highlight
ABSTRACT:
SUBMITTER: Jiang HL
PROVIDER: S-EPMC4599274 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Jiang Hong-Lin HL Sun He-Fen HF Gao Shui-Ping SP Li Liang-Dong LD Hu Xin X Wu Jiong J Jin Wei W
Oncotarget 20150601 18
Triple-negative breast cancer (TNBC) is a highly aggressive tumor subtype associated with a poor prognosis. The mechanism involved in TNBC progression remains largely unknown. To date, there are no effective therapeutic targets for this tumor subtype. In this study, by performing quantitative proteomic analyses in highly metastatic and parental breast cancer cell line, we found that RAB1B, a member of the RAS oncogene family, was significantly down-regulated in highly metastatic breast cancer ce ...[more]