Smart hydrogels containing adenylate kinase: translating substrate recognition into macroscopic motion.
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ABSTRACT:
SUBMITTER: Yuan W
PROVIDER: S-EPMC4599350 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Publications
Smart hydrogels containing adenylate kinase: translating substrate recognition into macroscopic motion.
Yuan Weiwei W Yang Jiyuan J Kopecková Pavla P Kopecek Jindrich J
Journal of the American Chemical Society 20081101 47
Enzyme-based hybrid hydrogels were prepared by covalently incorporating an adenylate kinase mutant, possessing two thiol groups, into HPMA copolymer- or PEG-based hydrogel structures. The nanoscale conformational change of enzyme, triggered by substrate recognition, translated into macroscopic motion of hydrogels. ...[more]
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