Ontology highlight
ABSTRACT:
SUBMITTER: Seidinger AL
PROVIDER: S-EPMC4599822 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Seidinger Ana Luiza AL Fortes Fernanda Paschoal FP Mastellaro Maria José MJ Cardinalli Izilda Aparecida IA Zambaldi Lilian Girotto LG Aguiar Simone Santos SS Yunes José Andrés JA
PloS one 20151009 10
The high incidence of adrenocortical tumors and choroid plexus carcinoma in children from South and Southeastern regions of Brazil is associated with the germline p.R337H mutation of TP53 gene. The concomitant occurrence of neuroblastoma and adrenocortical tumors in pediatric patients harboring the p.R337H mutation at our institution prompted us to investigate the putative association between p.R337H and pediatric neuroblastoma. Genomic DNA samples from 83 neuroblastoma patients referred to a si ...[more]