Empirical Estimation of R0 for Unknown Transmission Functions: The Case of Chronic Wasting Disease in Alberta.
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ABSTRACT:
SUBMITTER: Potapov A
PROVIDER: S-EPMC4599850 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Empirical Estimation of R0 for Unknown Transmission Functions: The Case of Chronic Wasting Disease in Alberta.
Potapov Alex A Merrill Evelyn E Pybus Margo M Lewis Mark A MA
PloS one 20151009 10
We consider the problem of estimating the basic reproduction number R0 from data on prevalence dynamics at the beginning of a disease outbreak. We derive discrete and continuous time models, some coefficients of which are to be fitted from data. We show that prevalence of the disease is sufficient to determine R0. We apply this method to chronic wasting disease spread in Alberta determining a range of possible R0 and their sensitivity to the probability of deer annual survival. ...[more]
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