A novel atlas of gene expression in human skeletal muscle reveals molecular changes associated with aging.
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ABSTRACT:
SUBMITTER: Su J
PROVIDER: S-EPMC4600214 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
A novel atlas of gene expression in human skeletal muscle reveals molecular changes associated with aging.
Su Jing J Ekman Carl C Oskolkov Nikolay N Lahti Leo L Ström Kristoffer K Brazma Alvis A Groop Leif L Rung Johan J Hansson Ola O
Skeletal muscle 20151009
<h4>Background</h4>Although high-throughput studies of gene expression have generated large amounts of data, most of which is freely available in public archives, the use of this valuable resource is limited by computational complications and non-homogenous annotation. To address these issues, we have performed a complete re-annotation of public microarray data from human skeletal muscle biopsies and constructed a muscle expression compendium consisting of nearly 3000 samples. The created muscle ...[more]
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