Ontology highlight
ABSTRACT:
SUBMITTER: Hyung S
PROVIDER: S-EPMC4601011 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Hyung Sujin S Yoon Lee Bo B Park Jong-Chul JC Kim Jinseok J Hur Eun-Mi EM Francis Suh Jun-Kyo JK
Scientific reports 20151012
A culture system that can recapitulate myelination in vitro will not only help us better understand the mechanism of myelination and demyelination, but also find out possible therapeutic interventions for treating demyelinating diseases. Here, we introduce a simple and reproducible myelination culture system using mouse motor neurons (MNs) and Schwann cells (SCs). Dissociated motor neurons are plated on a feeder layer of SCs, which interact with and wrap around the axons of MNs as they different ...[more]