When amyloids become prions.
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ABSTRACT:
SUBMITTER: Sabate R
PROVIDER: S-EPMC4601197 | biostudies-literature | 2014 May-Jun
REPOSITORIES: biostudies-literature
Publications
The conformational diseases, linked to protein aggregation into amyloid conformations, range from non-infectious neurodegenerative disorders, such as Alzheimer disease (AD), to highly infectious ones, such as human transmissible spongiform encephalopathies (TSEs). They are commonly known as prion diseases. However, since all amyloids could be considered prions (from those involved in cell-to-cell transmission to those responsible for real neuronal invasion), it is necessary to find an underlying ...[more]
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