Photovoltaic restoration of sight with high visual acuity.
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ABSTRACT:
SUBMITTER: Lorach H
PROVIDER: S-EPMC4601644 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Publications
Photovoltaic restoration of sight with high visual acuity.
Lorach Henri H Goetz Georges G Smith Richard R Lei Xin X Mandel Yossi Y Kamins Theodore T Mathieson Keith K Huie Philip P Harris James J Sher Alexander A Palanker Daniel D
Nature medicine 20150427 5
Patients with retinal degeneration lose sight due to the gradual demise of photoreceptors. Electrical stimulation of surviving retinal neurons provides an alternative route for the delivery of visual information. We demonstrate that subretinal implants with 70-μm-wide photovoltaic pixels provide highly localized stimulation of retinal neurons in rats. The electrical receptive fields recorded in retinal ganglion cells were similar in size to the natural visual receptive fields. Similarly to norma ...[more]
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