Ontology highlight
ABSTRACT:
SUBMITTER: Kuhn P
PROVIDER: S-EPMC4602035 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
The Journal of cell biology 20151001 1
Cotranslational protein targeting delivers proteins to the bacterial cytoplasmic membrane or to the eukaryotic endoplasmic reticulum membrane. The signal recognition particle (SRP) binds to signal sequences emerging from the ribosomal tunnel and targets the ribosome-nascent-chain complex (RNC) to the SRP receptor, termed FtsY in bacteria. FtsY interacts with the fifth cytosolic loop of SecY in the SecYEG translocon, but the functional role of the interaction is unclear. By using photo-cross-link ...[more]