Ontology highlight
ABSTRACT:
SUBMITTER: Sirois JJ
PROVIDER: S-EPMC4604600 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Sirois John J JJ DeBoef Brenton B
Tetrahedron letters 20151001 41
The formation of carbon-nitrogen (C-N) bonds via an umpolung substitution reaction has been achieved at -78 °C without the need for catalysts, ligands, or additives. The scope is limited to aryl Grignard reagents with N-chloroamines. The findings in this manuscript serve as a reference point for all C-N bond formation involving N-chloroamines and organometallic reagents. Knowing the yields of uncatalyzed reactions will be useful when determining the success of future catalytic methods. ...[more]