Investigating age-related changes in anterior and posterior neural activity throughout the information processing stream.

ABSTRACT: Event-related potential (ERP) and other functional imaging studies often demonstrate age-related increases in anterior neural activity and decreases in posterior activity while subjects carry out task demands. It remains unclear whether this "anterior shift" is limited to late cognitive operations like those indexed by the P3 component, or is evident during other stages of information processing. The temporal resolution of ERPs provided an opportunity to address this issue. Temporospatial principal component analysis (PCA) was used to identify underlying components that may be obscured by overlapping ERP waveforms. ERPs were measured during a visual oddball task in 26 young, 26 middle-aged, and 29 old subjects who were well-matched for IQ, executive function, education, and task performanc

SUBMITTER: Alperin BR 

PROVIDER: S-EPMC4605281 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature