Immune cell interplay in colorectal cancer prognosis.
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ABSTRACT:
SUBMITTER: Norton SE
PROVIDER: S-EPMC4606176 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Publications
Immune cell interplay in colorectal cancer prognosis.
Norton Samuel E SE Ward-Hartstonge Kirsten A KA Taylor Edward S ES Kemp Roslyn A RA
World journal of gastrointestinal oncology 20151001 10
The immune response to colorectal cancer has proven to be a reliable measure of patient outcome in several studies. However, the complexity of the immune response in this disease is not well understood, particularly the interactions between tumour-associated cells and cells of the innate and adaptive immune system. This review will discuss the relationship between cancer associated fibroblasts and macrophages, as well as between macrophages and T cells, and demonstrate how each population may su ...[more]
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