Prevalence of neurogenetic disorders in the North of England.
Ontology highlight
ABSTRACT: Objective
Genetic disorders enter the differential diagnosis of common neurologic diseases, but their overall prevalence is not known. We set out to determine their minimum prevalence.Methods
Meta-analysis of epidemiologic data gathered from the same geographic region in the North of England.Results
Monogenic neurologic disorders affect at least 90.9/100,000 (95% confidence interval 87.6-94.3), or 1 in 1,100 of the population in Northern England.Conclusion
As a group, neurogenetic disorders are not rare. These findings have implications for clinical service delivery.
SUBMITTER: Bargiela D
PROVIDER: S-EPMC4607600 | biostudies-literature |
REPOSITORIES: biostudies-literature
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