Ontology highlight
ABSTRACT:
SUBMITTER: Friesen WL
PROVIDER: S-EPMC4607658 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Friesen William L WL Schultz Brian J BJ Destino Joel F JF Alivio Theodore E G TE Steet Joseph R JR Banerjee Sarbajit S Wood Troy D TD
Journal of the American Society for Mass Spectrometry 20150901 11
Here, a matrix using two-dimensional (2D) graphene is demonstrated for the first time in the context of MALDI IMS using a Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer. Although graphene flakes have been used previously in MALDI, it is described here how a single 2D layer of graphene is applied directly on top of rat brain sections and soybean leaves. Several classes of molecules are desorbed and ionized off of the surface of the tissues examined using 2D graphene, with mi ...[more]