Manganese-Mediated Coupling Reaction of Vinylarenes and Aliphatic Alcohols.
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ABSTRACT: Alcohols and alkenes are the most abundant and commonly used organic building blocks in the large-scale chemical synthesis. Herein, this is the first time to report a novel and operationally simple coupling reaction of vinylarenes and aliphatic alcohols catalyzed by manganese in the presence of TBHP (tert-butyl hydroperoxide). This coupling reaction provides the oxyalkylated products of vinylarenes with good regioselectivity and accomplishes with the principles of step-economies. A possible reaction mechanism has also been proposed.
SUBMITTER: Zhang W
PROVIDER: S-EPMC4607950 | biostudies-literature |
REPOSITORIES: biostudies-literature
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