Ontology highlight
ABSTRACT:
SUBMITTER: Chen JM
PROVIDER: S-EPMC4608213 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Chen Jian-Ming JM Guo Jing J Wei Chuan-Dong CD Wang Chun-Fang CF Luo Hong-Cheng HC Wei Ye-Sheng YS Lan Yan Y
BMC genetics 20151016
<h4>Background</h4>Current evidence shows that the CD40-CD40 ligand (CD40-CD40L) system plays a crucial role in the development, progression and outcome of systemic lupus erythematosus (SLE). The aim of this study was to investigate whether a CD40 gene single nucleotide polymorphism (SNP) is associated with SLE and CD40 expression in the Chinese population. We included controls (n = 220) and patients with either SLE (n =205) in the study.<h4>Methods</h4>The gene polymorphism was measured using S ...[more]