SapFinder: an R/Bioconductor package for detection of variant peptides in shotgun proteomics experiments.
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ABSTRACT:
SUBMITTER: Wen B
PROVIDER: S-EPMC4609003 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Publications
sapFinder: an R/Bioconductor package for detection of variant peptides in shotgun proteomics experiments.
Wen Bo B Xu Shaohang S Sheynkman Gloria M GM Feng Qiang Q Lin Liang L Wang Quanhui Q Xu Xun X Wang Jun J Liu Siqi S
Bioinformatics (Oxford, England) 20140722 21
<h4>Unlabelled</h4>Single nucleotide variations (SNVs) located within a reading frame can result in single amino acid polymorphisms (SAPs), leading to alteration of the corresponding amino acid sequence as well as function of a protein. Accurate detection of SAPs is an important issue in proteomic analysis at the experimental and bioinformatic level. Herein, we present sapFinder, an R software package, for detection of the variant peptides based on tandem mass spectrometry (MS/MS)-based proteomi ...[more]
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