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M-Protein Analysis of Streptococcus pyogenes Isolates Associated with Acute Rheumatic Fever in New Zealand.

ABSTRACT: We applied an emm cluster typing system to group A Streptococcus strains in New Zealand, including those associated with acute rheumatic fever (ARF). We observed few so-called rheumatogenic emm types but found a high proportion of emm types previously associated with pyoderma, further suggesting a role for skin infection in ARF.

SUBMITTER: Williamson DA

PROVIDER: S-EPMC4609735 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature

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M-Protein Analysis of Streptococcus pyogenes Isolates Associated with Acute Rheumatic Fever in New Zealand.

Williamson Deborah A DA Smeesters Pierre R PR Steer Andrew C AC Steemson John D JD Ng Adrian C H AC Proft Thomas T Fraser John D JD Baker Michael G MG Morgan Julie J Carter Philip E PE Moreland Nicole J NJ

Journal of clinical microbiology 20150819 11

We applied an emm cluster typing system to group A Streptococcus strains in New Zealand, including those associated with acute rheumatic fever (ARF). We observed few so-called rheumatogenic emm types but found a high proportion of emm types previously associated with pyoderma, further suggesting a role for skin infection in ARF. ...[more]

PMID: 26292296

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